BDBM50257406 CHEMBL453807::His-Ala-Lys(epsilon-thioAc)Leu-Met

SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(O)=O

InChI Key InChIKey=CWOIIRRASFTQMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257406   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257406(His-Ala-Lys(epsilon-thioAc)Leu-Met | CHEMBL453807)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257406(His-Ala-Lys(epsilon-thioAc)Leu-Met | CHEMBL453807)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed