BDBM50257217 CHEMBL2323100

SMILES Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1nncs1

InChI Key InChIKey=LDRZWGWBOYORGD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257217   

LigandPNGBDBM50257217(CHEMBL2323100)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257217(CHEMBL2323100)
Affinity DataIC50: 244nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257217(CHEMBL2323100)
Affinity DataIC50: 240nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed