BDBM50257200 CHEMBL507676::Ser-Asp-Lys(epsilon-thioAc)-Thr-Ile

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(O)=O

InChI Key InChIKey=WRIWTGWVHVWDCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257200   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257200(Ser-Asp-Lys(epsilon-thioAc)-Thr-Ile | CHEMBL507676)
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257200(Ser-Asp-Lys(epsilon-thioAc)-Thr-Ile | CHEMBL507676)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed