BDBM50257157 CHEMBL4103356

SMILES Cc1ccc(cn1)-c1ccc(NC(=O)CN2CCCC3=C2C(=O)N(C2CC2)C3=O)nn1

InChI Key InChIKey=AWFKDFGAFDJYLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257157   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed