BDBM50257057 8-Bromo-9-(2-hydroxypropyl)-9H-adenine::CHEMBL475617

SMILES CC(O)Cn1c(Br)nc2c(N)ncnc12

InChI Key InChIKey=MMKXSEBGGSBLDX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257057   

TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50257057(8-Bromo-9-(2-hydroxypropyl)-9H-adenine | CHEMBL475...)
Affinity DataKi:  640nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50257057(8-Bromo-9-(2-hydroxypropyl)-9H-adenine | CHEMBL475...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50257057(8-Bromo-9-(2-hydroxypropyl)-9H-adenine | CHEMBL475...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed