BDBM50257051 2-(6-amino-8-bromo-9H-purin-9-yl)ethanol::8-Bromo-9-(2-hydroxyethyl)-9H-adenine::CHEMBL474058

SMILES Nc1ncnc2n(CCO)c(Br)nc12

InChI Key InChIKey=HPCQLQBYCLLETI-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50257051   

TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  620nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  620nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  620nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  1.50E+3nMAssay Description:Antagonist activity against human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  2.80E+3nMAssay Description:Antagonist activity against human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  2.80E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi:  2.80E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi: >1.00E+5nMAssay Description:Antagonist activity against human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50257051(2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed