BDBM50256975 (4-(2-aminophenylcarbamoyl)benzylamino)methyl nicotinate::CHEMBL514671

SMILES Nc1ccccc1NC(=O)c1ccc(CNCOC(=O)c2cccnc2)cc1

InChI Key InChIKey=YPFKJHJILXIYNQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50256975   

TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256975((4-(2-aminophenylcarbamoyl)benzylamino)methyl nico...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256975((4-(2-aminophenylcarbamoyl)benzylamino)methyl nico...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256975((4-(2-aminophenylcarbamoyl)benzylamino)methyl nico...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild-type c-Abl by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256975((4-(2-aminophenylcarbamoyl)benzylamino)methyl nico...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256975((4-(2-aminophenylcarbamoyl)benzylamino)methyl nico...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256975((4-(2-aminophenylcarbamoyl)benzylamino)methyl nico...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Flag tagged human recombinant HDAC3 expressed in Sf21 cells coexpressing SMRT DAD domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed