BDBM50256950 8-Bromo-9-isobutyl-9H-adenine::8-bromo-9-isobutyl-9H-purin-6-amine::CHEMBL474207

SMILES CC(C)Cn1c(Br)nc2c(N)ncnc12

InChI Key InChIKey=RLPKQFORPDRBQT-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50256950   

TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  4.20E+3nMAssay Description:Antagonist activity against human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  4.20E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  4.90E+3nMAssay Description:Antagonist activity against human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  6.00E+3nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  1.50E+4nMAssay Description:Antagonist activity against human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50256950(8-bromo-9-isobutyl-9H-purin-6-amine | 8-Bromo-9-is...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed