BDBM50256931 CHEMBL1186032

SMILES [H][C@@]12CCC=C(COC(=O)c3ccc[nH]3)[C@]1(C)CC[C@H](C)[C@@]2(C)CC\C(C)=C\Cn1c[n+](C)c2ncnc(N)c12

InChI Key InChIKey=NNJSZZQHXOEUSF-UHFFFAOYSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50256931   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant TCPTP (1 to 317 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant CD45 using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed