BDBM50256734 (-)-Cercosporamide::CHEMBL475816

SMILES CC(=O)C1C(=O)C=C2Oc3c(c(O)cc(O)c3C(N)=O)[C@]2(C)C1=O

InChI Key InChIKey=VUZOCQCFKZJNJC-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50256734   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant human CDK2/Cyclin A using ATP and Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 38nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 43nMAssay Description:Inhibition of human lung HIS-tagged Mnk1 transfected in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CLK1 using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig GSK3beta using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
Target[Tau protein] kinase(Pig)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig GSK3alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 60 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human haspin using full-length histone H3 as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human Aurora-B using full-length histone H3 as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 300nMAssay Description:Inhibition of human PKCbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human PKCalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human PIM1 using CREBtide as substrate after 60 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human CDK9/CyclinT using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetCasein kinase 1, delta tv1(Pig)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig CK1deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat Dyrk1a using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Pig)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig CK1epsilon using Ulight-ARTKQTARKSTGGKAPRKQLAGCG as substrate after 60 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human PKCgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 350nMAssay Description:Inhibition of human PKCbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C-like 1(Yeast)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 44nMAssay Description:Inhibition of Candida albicans Pkc1 expressed in insect Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed