BDBM50256229 CHEMBL4063752

SMILES C[C@H]1CN(CCN1c1ncc(cn1)C(F)(F)F)C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

InChI Key InChIKey=WKCWHWQATMIGEI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256229   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Shionogi

Curated by ChEMBL

LigandBDBM50256229(CHEMBL4063752)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/9/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Shionogi

Curated by ChEMBL

LigandBDBM50256229(CHEMBL4063752)Copy SMILESCopy InChI

Affinity DataIC50: 47nMAssay Description:Antagonist activity at recombinant rat TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins fo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/9/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL