BDBM50256088 CHEMBL4065589

SMILES COc1cccc(Nc2cc(nc3CCNC(=O)c23)-c2cccc(Sc3cccc(OC)c3)c2)c1

InChI Key InChIKey=WZURXNJCGHFFJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256088   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50256088(CHEMBL4065589)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human PDE4B1 using [3H]-cAMP as substrate preincubated for 15 mins followed substrate addition measured after 60 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2019
Entry Details Article
PubMed