BDBM50255987 CHEMBL4064370

SMILES COc1cccc(c1)Nc2cc(nc3c2C(=O)NCC3)c4ccccc4

InChI Key InChIKey=PBJZBHKLXZKPND-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255987   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50255987(CHEMBL4064370)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human PDE4B1 using [3H]-cAMP as substrate preincubated for 15 mins followed substrate addition measured after 60 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)