BDBM50255943 CHEMBL482330::N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide

SMILES COc1cccc(CN2C(=O)CC3(C)CCCC(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)=C23)c1

InChI Key InChIKey=KLSVHZDRIZUKOZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255943   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 12.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity to human EP1 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 7.50E+3nMAssay Description:Binding affinity to human EP4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 6.40E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed