BDBM50255913 CHEMBL481726::N-hydroxy-4-(((R)-3,6-dioxo-2-((thiophen-2-yl)methyl)piperazin-1-yl)methyl)benzamide

SMILES ONC(=O)c1ccc(CN2[C@H](Cc3cccs3)C(=O)NCC2=O)cc1

InChI Key InChIKey=MLRJDCCBCWNZMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255913   

TargetHistone deacetylase 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255913(N-hydroxy-4-(((R)-3,6-dioxo-2-((thiophen-2-yl)meth...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of human recombinant histone deacetylase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255913(N-hydroxy-4-(((R)-3,6-dioxo-2-((thiophen-2-yl)meth...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255913(N-hydroxy-4-(((R)-3,6-dioxo-2-((thiophen-2-yl)meth...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant histone deacetylase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed