BDBM50255912 4-(((R)-2-((1H-indol-3-yl)methyl)-3,6-dioxopiperazin-1-yl)methyl)-N-hydroxybenzamide::CHEMBL481719

SMILES ONC(=O)c1ccc(CN2[C@H](Cc3c[nH]c4ccccc34)C(=O)NCC2=O)cc1

InChI Key InChIKey=PELASOGQJSUMMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255912   

TargetHistone deacetylase 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255912(4-(((R)-2-((1H-indol-3-yl)methyl)-3,6-dioxopiperaz...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of human recombinant histone deacetylase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255912(4-(((R)-2-((1H-indol-3-yl)methyl)-3,6-dioxopiperaz...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255912(4-(((R)-2-((1H-indol-3-yl)methyl)-3,6-dioxopiperaz...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human recombinant histone deacetylase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed