BDBM50255901 1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(methylsulfonyl)phenyl]-1H-benzimidazole::CHEMBL481367

SMILES CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=ZJQLCFIUFKGFMA-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255901   

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255901(1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(met...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255901(1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(met...)
Affinity DataEC50:  288nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255901(1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(met...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255901(1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(met...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed