BDBM50255723 CHEMBL481813::N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3a-methyl-1-(naphthalen-2-ylmethyl)-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide

SMILES CC12CC(=O)N(Cc3ccc4ccccc4c3)C1=C(CCC2)\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1

InChI Key InChIKey=HRHVVNHNDMQNFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255723   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255723(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3a-methyl...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255723(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3a-methyl...)
Affinity DataIC50: 6.90E+3nMAssay Description:Binding affinity to human EP1 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255723(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3a-methyl...)
Affinity DataIC50: 1.02E+4nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed