BDBM50255643 4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carboxamide::CHEMBL481402

SMILES COc1cc2ncc(C(N)=O)c(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=CYOGHJXLSFPFGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255643   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255643(4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-(3-(4...)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed