BDBM50255588 4-(3-chloro-4-fluorophenylamino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carboxamide::CHEMBL481231

SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cc1OCCCN1CCN(C)CC1)C(N)=O

InChI Key InChIKey=YWVGLEXQTHLLMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255588   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255588(4-(3-chloro-4-fluorophenylamino)-6-methoxy-7-(3-(4...)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed