BDBM50255545 CHEMBL4097602

SMILES CN(C)[C@H]1C[C@@H](C1)S(=O)(=O)c1c(Cl)ccc(NC(=O)N[C@@H]2CCC=C2C)c1O

InChI Key InChIKey=UADSESNXJPFVMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255545   

TargetC-X-C chemokine receptor type 2(Human)
Gsk Pharmaceuticals R & D

Curated by ChEMBL
LigandPNGBDBM50255545(CHEMBL4097602)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at CXCR2 in human whole blood assessed as inhibition of GROalpha-stimulated CD11b upregulation preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Gsk Pharmaceuticals R & D

Curated by ChEMBL
LigandPNGBDBM50255545(CHEMBL4097602)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as inhibition of TEV pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMed