BDBM50255459 CHEMBL4084077

SMILES COCC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)N[C@@H]2CCC=C2C)c1O

InChI Key InChIKey=VQEVJSPNOJTBSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255459   

TargetC-X-C chemokine receptor type 2(Human)
Gsk Pharmaceuticals R & D

Curated by ChEMBL
LigandPNGBDBM50255459(CHEMBL4084077)
Affinity DataIC50: 398nMAssay Description:Antagonist activity at CXCR2 in human whole blood assessed as inhibition of GROalpha-stimulated CD11b upregulation preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Gsk Pharmaceuticals R & D

Curated by ChEMBL
LigandPNGBDBM50255459(CHEMBL4084077)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as inhibition of TEV pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMed