BDBM50255380 (S)-N-(4-tert-butylphenyl)-1-oxo-2,3-diphenyl-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL479645

SMILES CC(C)(C)c1ccc(NC(=O)N2CCC3(CC2)[C@@H](N(C3=O)c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=MCACKYGWBBVINR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255380   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50255380((S)-N-(4-tert-butylphenyl)-1-oxo-2,3-diphenyl-2,7-...)
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50255380((S)-N-(4-tert-butylphenyl)-1-oxo-2,3-diphenyl-2,7-...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of PMA-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed