BDBM50255233 1-(4-Aminosulfonylphenyl)-2-[5-(1-difluoromethylpyrid-2-one)]acetylene::4-((1-(difluoromethyl)-6-oxo-1,6-dihydropyridin-3-yl)ethynyl)benzenesulfonamide::CHEMBL447148

SMILES NS(=O)(=O)c1ccc(cc1)C#Cc1ccc(=O)n(c1)C(F)F

InChI Key InChIKey=NGMLZRLOVANOEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255233   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50255233(4-((1-(difluoromethyl)-6-oxo-1,6-dihydropyridin-3-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50255233(4-((1-(difluoromethyl)-6-oxo-1,6-dihydropyridin-3-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed