BDBM50255219 (+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(trifluoromethyl)benzamido)acetamido)cyclohexylcarbamate::(+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(trifluoromethyl)benzamido)acetamido)cyclohexylcarbamate::CHEMBL505722

SMILES CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1

InChI Key InChIKey=LAPGFBUSBADRJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255219   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 7nMAssay Description:Inhibition of CCR3 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed