BDBM50255154 CHEMBL1277694::CHEMBL516764::N1-{(+/-)-4'-[(6''-amino-4''-methylpyridin-2''-yl)methyl]pyrrolidin-3'-yl}-N2-(4'-chlorobenzyl)-N1-methylethane-1,2-diamine

SMILES CN(CCNCc1ccc(Cl)cc1)[C@@H]1CNC[C@@H]1Cc1cc(C)cc(N)n1

InChI Key InChIKey=PDIFIRUKOSADNL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50255154   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255154(CHEMBL516764 | CHEMBL1277694 | N1-{(+/-)-4'-[(6''-...)
Affinity DataKi:  393nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255154(CHEMBL516764 | CHEMBL1277694 | N1-{(+/-)-4'-[(6''-...)
Affinity DataKi:  1.89E+3nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255154(CHEMBL516764 | CHEMBL1277694 | N1-{(+/-)-4'-[(6''-...)
Affinity DataKi:  2.28E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255154(CHEMBL516764 | CHEMBL1277694 | N1-{(+/-)-4'-[(6''-...)
Affinity DataKi:  5.81E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255154(CHEMBL516764 | CHEMBL1277694 | N1-{(+/-)-4'-[(6''-...)
Affinity DataKi:  7.54E+4nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255154(CHEMBL516764 | CHEMBL1277694 | N1-{(+/-)-4'-[(6''-...)
Affinity DataKi:  1.25E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed