BDBM50254791 (R)-Norfluoxetine::CHEMBL446084

SMILES c1ccc(cc1)[C@@H](CCN)Oc2ccc(cc2)C(F)(F)F

InChI Key InChIKey=WIQRCHMSJFFONW-UHFFFAOYSA-N

Data  3 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50254791   

TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)
Affinity DataKi:  3.66E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)
Affinity DataKi:  7.49E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed