BDBM50254701 6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide::CHEMBL480398

SMILES Brc1cccc(Nc2cc(C3CC3)c(cn2)C(=O)NCC2CCOCC2)c1

InChI Key InChIKey=MFMYBHHGKONKNN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254701   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254701(6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydr...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254701(6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254701(6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydr...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254701(6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydr...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP1A2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254701(6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydr...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed