BDBM50254484 3-(dimethylamino)butyl ethylcarbamate::CHEMBL451633

SMILES CCNC(=O)OCCC(C)N(C)C

InChI Key InChIKey=IXIGRKFDMBWCOA-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254484   

TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254484(3-(dimethylamino)butyl ethylcarbamate | CHEMBL4516...)
Affinity DataEC50:  5.01E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254484(3-(dimethylamino)butyl ethylcarbamate | CHEMBL4516...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254484(3-(dimethylamino)butyl ethylcarbamate | CHEMBL4516...)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254484(3-(dimethylamino)butyl ethylcarbamate | CHEMBL4516...)
Affinity DataKi:  1.26E+4nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254484(3-(dimethylamino)butyl ethylcarbamate | CHEMBL4516...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]MLA from alpha7 nAChR/5HT3A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed