BDBM50254447 1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::CHEMBL468695

SMILES CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O

InChI Key InChIKey=UKCCRJLNYAYHBT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254447   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluor...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed