BDBM50254444 6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide::CHEMBL466191

SMILES CC(C)c1cc(Nc2ccc(Cl)cc2Cl)ncc1C(=O)NCC1CCOCC1

InChI Key InChIKey=YIJJJJWZXATIQL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254444   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254444(6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrah...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254444(6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrah...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254444(6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrah...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254444(6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrah...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of CYP1A2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254444(6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrah...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed