BDBM50254421 CHEMBL465990::N7-(3-chloro-4-(trifluoromethyl)phenyl)-N2-(2,6-dichlorophenyl)-5-methylthiazolo[5,4-d]pyrimidine-2,7-diamine

SMILES Cc1nc(Nc2ccc(c(Cl)c2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1

InChI Key InChIKey=YBYZWKCBDRTNOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254421   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50254421(N7-(3-chloro-4-(trifluoromethyl)phenyl)-N2-(2,6-di...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50254421(N7-(3-chloro-4-(trifluoromethyl)phenyl)-N2-(2,6-di...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed