BDBM50254399 CHEMBL6092038

SMILES Cn1cc(-c2ccc3nc(C4CCOCC4)[nH]c3c2Oc2ccccc2)ccc1=O

InChI Key InChIKey=WMAFFYWORUSDEA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50254399   

TargetBromodomain-containing protein 4(Human)
Maruho Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254399BDBM50254399(CHEMBL6092038)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Maruho Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254399BDBM50254399(CHEMBL6092038)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Maruho Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254399BDBM50254399(CHEMBL6092038)
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Maruho Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254399BDBM50254399(CHEMBL6092038)
Affinity DataIC50: 20nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Maruho Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254399BDBM50254399(CHEMBL6092038)
Affinity DataIC50: 22nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Maruho Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254399BDBM50254399(CHEMBL6092038)
Affinity DataIC50: 114nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed