BDBM50254364 (+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4'-methoxy-biphenyl-3-sulfonylamino)-3-oxo-propyl]-benzamidine::CHEMBL460378

SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1

InChI Key InChIKey=VXKCYOLSCMFIDJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254364   

TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254364((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  7nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254364((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254364((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  120nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254364((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  360nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254364((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed