BDBM50254331 6,7'-oxybis(2-(2,4-dimethoxyphenyl)-4H-chromen-4-one)::CHEMBL447655

SMILES COc1ccc(c(OC)c1)-c1cc(=O)c2cc(Oc3ccc4c(c3)oc(cc4=O)-c3ccc(OC)cc3OC)ccc2o1

InChI Key InChIKey=GNPMTDCRJKGIED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254331   

TargetProstaglandin G/H synthase 2(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254331(6,7'-oxybis(2-(2,4-dimethoxyphenyl)-4H-chromen-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254331(6,7'-oxybis(2-(2,4-dimethoxyphenyl)-4H-chromen-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed