BDBM50254219 Azetidine-3-carboxylic acid {3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(3-carbamimidoyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-amide::CHEMBL461870::US8569313, 71

SMILES NCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)C2CNC2)c1

InChI Key InChIKey=NDNZSZVYHIQKKQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50254219   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50254219(US8569313, 71 | CHEMBL461870 | Azetidine-3-carboxy...)
Affinity DataKi:  1.70nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50254219(US8569313, 71 | CHEMBL461870 | Azetidine-3-carboxy...)
Affinity DataKi:  3nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254219(US8569313, 71 | CHEMBL461870 | Azetidine-3-carboxy...)
Affinity DataKi:  500nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254219(US8569313, 71 | CHEMBL461870 | Azetidine-3-carboxy...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254219(US8569313, 71 | CHEMBL461870 | Azetidine-3-carboxy...)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254219(US8569313, 71 | CHEMBL461870 | Azetidine-3-carboxy...)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed