BDBM50254044 CHEMBL540704::N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanamide

SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccccc3F)ccc12

InChI Key InChIKey=BVIHFTLHUNNBFZ-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50254044   

TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50:  111nMAssay Description:Agonist activity at human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50: >2.00E+3nMAssay Description:Agonist activity at human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50254044(N-(9-ethyl-9H-carbazol-3-yl)-3-(3-(2-fluorophenyl)...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed