BDBM50253954 3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(3-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide::CHEMBL459525::US8569313, 61

SMILES NCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(CN)c1)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key InChIKey=FHYYSYMCUOCQDL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253954   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50253954(CHEMBL459525 | US8569313, 61 | 3-Amino-N-{3-[(S)-2...)
Affinity DataKi:  56nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50253954(CHEMBL459525 | US8569313, 61 | 3-Amino-N-{3-[(S)-2...)
Affinity DataKi:  56nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50253954(CHEMBL459525 | US8569313, 61 | 3-Amino-N-{3-[(S)-2...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50253954(CHEMBL459525 | US8569313, 61 | 3-Amino-N-{3-[(S)-2...)
Affinity DataKi:  9.20E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50253954(CHEMBL459525 | US8569313, 61 | 3-Amino-N-{3-[(S)-2...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50253954(CHEMBL459525 | US8569313, 61 | 3-Amino-N-{3-[(S)-2...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed