BDBM50253941 3-((1H-imidazol-1-yl)(4-nitrophenyl)methyl)-4H-chromen-4-one::3-[Imidazol-1-yl-(4-nitro-phenyl)-methyl]-chromen-4-one::CHEMBL516643

SMILES [O-][N+](=O)c1ccc(cc1)C(c1coc2ccccc2c1=O)n1ccnc1

InChI Key InChIKey=GQUCRMYPRQVAIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253941   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253941(3-((1H-imidazol-1-yl)(4-nitrophenyl)methyl)-4H-chr...)
Affinity DataIC50: 187nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253941(3-((1H-imidazol-1-yl)(4-nitrophenyl)methyl)-4H-chr...)
Affinity DataIC50: 152nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50253941(3-((1H-imidazol-1-yl)(4-nitrophenyl)methyl)-4H-chr...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed