BDBM50253916 CHEMBL461427::N-(Azepan-1-yl)-5-(5-(but-1-ynyl)thiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

SMILES CCC#Cc1ccc(s1)-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCCC1

InChI Key InChIKey=GNVYTDPQYLDLJV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253916   

TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253916(N-(Azepan-1-yl)-5-(5-(but-1-ynyl)thiophen-2-yl)-1-...)
Affinity DataIC50: 24.2nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253916(N-(Azepan-1-yl)-5-(5-(but-1-ynyl)thiophen-2-yl)-1-...)
Affinity DataIC50: 1.06E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253916(N-(Azepan-1-yl)-5-(5-(but-1-ynyl)thiophen-2-yl)-1-...)
Affinity DataEC50:  36.4nMAssay Description:Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed