BDBM50253899 CHEMBL512630::Ethyl 4-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-6-yl}amino)-4-oxobutanoate trifluoroacetate

SMILES CCOC(=O)CCC(=O)N(Cc1ccccc1)c1ccc2OC(C)(COc3ccc(cc3)C(N)=N)CN(C)c2c1

InChI Key InChIKey=MTTOKWJETCFANC-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253899   

TargetIntegrin alpha-IIb(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253899(Ethyl 4-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of fibrinogen binding to human platelet GPIIb/IIIa receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253899(Ethyl 4-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]...)
Affinity DataKi:  670nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253899(Ethyl 4-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]...)
Affinity DataKi:  2.77E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed