BDBM50253610 (3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethoxyphenyl)-methanone::CHEMBL492892

SMILES FC(F)(F)Oc1ccc(cc1)C(=O)c1cc2ccccc2cc1-c1cccnc1

InChI Key InChIKey=NCJRHWNXUZJLDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253610   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253610((3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethox...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253610((3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethox...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed