BDBM50253587 1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxyprop-1-ynyl)-thiophen-2-yl]-1H-pyrazole-3-carboxylic Acid Piperidin-1-ylamide::CHEMBL523872

SMILES Cc1c(nn(c1-c1ccc(s1)C#CCOc1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1

InChI Key InChIKey=SYYJKQJOSWHETE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253587   

TargetCannabinoid receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253587(1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxypro...)
Affinity DataIC50: 7.03E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253587(1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxypro...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253587(1-(2,4-Dichlorophenyl)-4-methyl-5-[5-(3-phenoxypro...)
Affinity DataEC50:  18.7nMAssay Description:Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed