BDBM50253331 CHEMBL4072215

SMILES O=C1C\C(=N/Nc2nc(cs2)-c2cccc(c2)C#N)c2ccccc12

InChI Key InChIKey=NULNAKJYFWFQIT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253331   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50253331(CHEMBL4072215)
Affinity DataEC50:  1.25E+4nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50253331(CHEMBL4072215)
Affinity DataIC50: 9.78E+3nMAssay Description:Inhibition of recombinant human His-tagged IDO1 expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of kynurenine production using L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed