BDBM50253296 CHEMBL4079351

SMILES Oc1cccc(c1)-c1csc(N\N=C2/CC(=O)c3ccccc23)n1

InChI Key InChIKey=IJUOIRMCCFIGCW-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253296   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50253296(CHEMBL4079351)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of human IDO expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of kynurenine production using L-tryptophan as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50253296(CHEMBL4079351)
Affinity DataEC50:  9.17E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50253296(CHEMBL4079351)
Affinity DataKd:  9.83E+3nMAssay Description:Binding affinity to human IDO1 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed