BDBM50253169 1,3-bis(5-hydroxy-7-{[3-(hydroxymethyl)phenyl]sulfamoyl}naphthalen-2-yl)urea::CHEMBL458241

SMILES OCc1cccc(NS(=O)(=O)c2cc(O)c3ccc(NC(=O)Nc4ccc5c(O)cc(cc5c4)S(=O)(=O)Nc4cccc(CO)c4)cc3c2)c1

InChI Key InChIKey=VUEPYTOWAFSBTM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253169   

TargetInsulin receptor(Mouse)
Telik

Curated by ChEMBL
LigandPNGBDBM50253169(1,3-bis(5-hydroxy-7-{[3-(hydroxymethyl)phenyl]sulf...)
Affinity DataEC50: >2.00E+5nMAssay Description:Activation of insulin receptor tyrosine kinase in mouse 3T3-L1 cells assessed as increase in 2-deoxy-D-[14C]glucose transport in presence of insulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed