BDBM50253168 1,3-bis(7-{[3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]sulfamoyl}naphthalen-2-yl)urea::CHEMBL454192

SMILES O=C(Nc1ccc2ccc(cc2c1)S(=O)(=O)Nc1cccc(c1)-n1cnnn1)Nc1ccc2ccc(cc2c1)S(=O)(=O)Nc1cccc(c1)-n1cnnn1

InChI Key InChIKey=MGOKCQQDJREPSG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253168   

TargetInsulin receptor(Mouse)
Telik

Curated by ChEMBL
LigandPNGBDBM50253168(1,3-bis(7-{[3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]sul...)
Affinity DataEC50:  5.40E+4nMAssay Description:Activation of insulin receptor tyrosine kinase in mouse 3T3-L1 cells assessed as increase in 2-deoxy-D-[14C]glucose transport in presence of insulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed