BDBM50253069 (1R,2R)-N-(1-cyanocyclopropyl)-5,5-difluoro-2-(1-methyl-4-(4-(methylsulfonyl)phenyl)-1H-pyrazol-3-yl)cyclohexanecarboxamide::CHEMBL523836

SMILES Cn1cc(c(n1)[C@@H]1CCC(F)(F)C[C@H]1C(=O)NC1(CC1)C#N)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=SPPYGIZTMGWBEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253069   

TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50253069((1R,2R)-N-(1-cyanocyclopropyl)-5,5-difluoro-2-(1-m...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed