BDBM50253009 2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methylthieno[2,3-d]pyrimidin-4(3H)-one::CHEMBL492837

SMILES COc1ccc(OC)c(Sc2c(C)[nH]c3nc(N)[nH]c(=O)c23)c1

InChI Key InChIKey=IKLXSHDEPYGLRG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253009   

TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253009(2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253009(2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253009(2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methyl...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253009(2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methyl...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253009(2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methyl...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253009(2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-methyl...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Toxoplasma gondii DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed