BDBM50253006 2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-d]pyrimidine::CHEMBL494067

SMILES Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccccc1

InChI Key InChIKey=JFGQRULHEDULON-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253006   

TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253006(2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253006(2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253006(2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253006(2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253006(2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253006(2-Amino-4-oxo-6-methyl-5-phenylsulfanylthieno[2,3-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Toxoplasma gondii DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed